TB Speed

diagnostic tests
glmm
Executed for

UMI 233 TransVIHMI

Published

August 23, 2024

Goal

The TB-Speed project carried out research activities aiming at reducing childhood mortality from TB by evaluating innovative and cost-effective TB diagnostic approaches for resource-limited settings. It has been implemented in seven countries of Africa and Asia: Cambodia, Cameroon, Côte d’Ivoire, Mozambique, Sierra Leone, Uganda, and Zambia, and contributed to screen more than 77000 children.

More info

Activities

Support on Output 1 “Decentralization study” and 4 “Stool processing study”

  • Data model, extraction, cleaning and transformation
  • Statistical analysis : mixed models, diagnostics test performance, Venn diagram
  • Assisting PhD student
  • Drafting articles

Articles

Lounnas, Manon, Eden Ngu Masama, Samuel Beneteau, Kunda Kasakwa, Rodney Kaitano, Pamela Nabeta, Morten Ruhwald, et al. 2025. “Centrifuge-Free Stool Processing Methods for Xpert MTB/RIF Ultra Tuberculosis Diagnosis in Children in Uganda and Zambia: An Observational, Prospective, Diagnostic Accuracy Study.” The Lancet Microbe, June, 101055. https://doi.org/10.1016/j.lanmic.2024.101055.
Melingui, B. F., E. Leroy-Terquem, M. Palmer, J-V. Taguebue, A. P. Wachinou, J. Gaudelus, A. Salomao, et al. 2024. “Evaluation of a Short Training Course of Chest x-Ray Interpretation for the Diagnosis of Paediatric TB.” IJTLD OPEN 1 (2): 76–82. https://doi.org/doi:10.5588/ijtldopen.23.0484.
Melingui, B. F., E. Leroy-Terquem, J. V. Taguebue, T. C. Eap, L. Borand, C. Khosa, R. Moh, et al. 2024. “External Quality Assurance of Chest x-Ray Interpretation to Strengthen Diagnosis of Childhood TB.” IJTLD OPEN 1 (10): 449–55. https://doi.org/doi:10.5588/ijtldopen.24.0328.
Melingui, Bernard Fortune, Joshi Basant, Jean voisin Taguebue, Douglas Mbang Massom, Etienne Leroy Terquem, Pierre Yves Norval, Angelica Salomao, et al. 2024. “Implementation of Digital Chest Radiography for Childhood Tuberculosis Diagnosis at District Hospital Level in Six High Tuberculosis Burden and Resources Limited Countries.” Tropical Medicine & International Health 29 (11): 979–89. https://doi.org/https://doi.org/10.1111/tmi.14053.

Partners

Activities realized for:

Institut de Recherche pour le Développement

Find all project partners here.

Photos

IRD - Samuel Beneteau

IRD - Samuel Beneteau